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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jon Byram* | 577 | 2029-2044 | |
| 2 | Lance Thomas* | 528 | 2043-2061 | |
| 3 | Germán Ramos# | 511 | 2051-2066 | |
| 4 | Sancho Rojas* | 491 | 2034-2053 | |
| 5 | Manny Gonzáles | 468 | 2028-2044 | |
| 6 | Bill Casselman* | 426 | 2023-2035 | |
| 7 | Larry Tomlinson | 412 | 2043-2061 | |
| 8 | José Encarnación# | 397 | 2051-2066 | |
| 9 | Martín González* | 373 | 2031-2045 | |
| 10 | Jon Vaughn# | 366 | 2057-2066 | |
| 11 | Benny Johnson | 351 | 2045-2060 | |
| 12 | William Reyes | 348 | 2023-2031 | |
| 13 | Ron Monroe | 343 | 2043-2058 | |
| 14 | William Stadler* | 339 | 2023-2044 | |
| 15 | Kirk Veeck# | 317 | 2057-2066 | |
| 16 | Michael Holbrook | 275 | 2029-2040 | |
| 17 | Orlando Moreno | 263 | 2040-2052 | |
| 18 | Daniel Oliveros | 261 | 2023-2030 | |
| 19 | Mark Davis | 253 | 2056-2063 | |
| 20 | Miguel Angel Campos# | 243 | 2062-2066 | |
| 21 | Kyoichi Matsumoto* | 239 | 2040-2057 | |
| 22 | Pedro Cabello | 236 | 2024-2037 | |
| 23 | Jason Mills* | 233 | 2043-2053 | |
| 24 | Juan Díaz# | 228 | 2056-2065 | |
| 25 | Brian Courtney | 226 | 2034-2047 | |
| 26 | José Reyes | 220 | 2029-2039 | |
| 27 | António Trevino | 216 | 2038-2049 | |
| 28 | Frank Stagg# | 215 | 2058-2066 | |
| 29 | Dan Calhoun | 209 | 2037-2043 | |
| 29 | John Laing | 209 | 2025-2040 | |
| 31 | Lorne Jennings | 208 | 2048-2056 | |
| 32 | Emanuel Campos | 205 | 2026-2041 | |
| 33 | Wilbur Bowles | 199 | 2033-2050 | |
| 34 | Bernardo Díaz* | 197 | 2041-2055 | |
| 35 | Desmond Reynolds | 191 | 2059-2064 | |
| 36 | Stanford Moore | 187 | 2030-2039 | |
| 37 | Jon Anderson | 183 | 2034-2042 | |
| 37 | Juan Pineda | 183 | 2024-2030 | |
| 39 | Jason Holt | 182 | 2029-2042 | |
| 40 | Robert Yedinak* | 172 | 2024-2044 | |
| 41 | Jack Mowrer* | 170 | 2025-2033 | |
| 41 | Daniel Pierson | 170 | 2042-2052 | |
| 43 | Javier López# | 167 | 2058-2066 | |
| 44 | Steve Blackwell | 166 | 2037-2048 | |
| 45 | Marlon McGrath# | 158 | 2048-2065 | |
| 46 | Frank Blackwell | 157 | 2023-2033 | |
| 46 | Jason Hazlett | 157 | 2026-2032 | |
| 48 | Juan Bernal# | 156 | 2057-2066 | |
| 49 | Andrew Elkins | 154 | 2049-2055 | |
| 50 | Leon Raposa | 153 | 2023-2031 | |
| 51 | Ramón Rodríguez | 151 | 2053-2059 | |
| 52 | Castor Hernandez | 145 | 2023-2030 | |
| 53 | Fernando Escalante | 143 | 2035-2040 | |
| 54 | Roscoe Bouldin | 142 | 2026-2033 | |
| 54 | Stephen Godwin# | 142 | 2060-2064 | |
| 56 | Eugene Hale | 141 | 2032-2040 | |
| 56 | Mario Rodríguez | 141 | 2050-2056 | |
| 58 | José Hernández* | 139 | 2032-2047 | |
| 59 | Chris Collins | 138 | 2040-2043 | |
| 59 | Alejandro Martínez | 138 | 2046-2055 | |
| 59 | Shohei Nishida# | 138 | 2049-2065 | |
| 62 | Carl Kelly | 137 | 2041-2054 | |
| 63 | Geoff Morris# | 134 | 2062-2066 | |
| 64 | Jarred Douglas | 133 | 2050-2064 | |
| 65 | Adam Sherman | 128 | 2050-2063 | |
| 66 | Dave Moore# | 126 | 2051-2055 | |
| 67 | Joe Kennedy | 123 | 2033-2047 | |
| 68 | Bennie Forshee | 122 | 2024-2030 | |
| 69 | Félix Ruíz# | 120 | 2061-2066 | |
| 70 | Buddy de Rijk# | 119 | 2055-2058 | |
| 71 | John Tunstall | 118 | 2023-2029 | |
| 72 | Carlos Gutiérrez | 114 | 2028-2042 | |
| 72 | Gil Moore | 114 | 2047-2052 | |
| 74 | José Espinoza | 111 | 2034-2044 | |
| 74 | Javier Martínez | 111 | 2043-2050 | |
| 76 | Ross Allen | 110 | 2045-2057 | |
| 77 | Kel Adams | 109 | 2053-2060 | |
| 78 | Juan Flores | 107 | 2036-2042 | |
| 78 | Pedro Otero | 107 | 2045-2051 | |
| 80 | Earl Oglethorpe# | 105 | 2054-2066 | |
| 81 | Carmelo Carballosa | 97 | 2024-2036 | |
| 82 | Ramón Castillo | 95 | 2045-2054 | |
| 82 | José Ortíz | 95 | 2049-2054 | |
| 84 | William Brady | 93 | 2029-2043 | |
| 84 | Lonnie Jackson | 93 | 2046-2060 | |
| 86 | Miguel Herrera# | 92 | 2063-2065 | |
| 86 | Luis Marrero | 92 | 2034-2042 | |
| 86 | Ben Martin | 92 | 2032-2040 | |
| 89 | Carlos Sarabia | 91 | 2023-2026 | |
| 89 | Vance Shields | 91 | 2054-2061 | |
| 91 | Gabriel Ramírez | 87 | 2036-2046 | |
| 92 | Nick Owens# | 86 | 2056-2065 | |
| 93 | David Britton# | 85 | 2061-2066 | |
| 93 | Ronald Montero | 85 | 2025-2028 | |
| 95 | Javier Gómez | 84 | 2053-2058 | |
| 96 | Javier Medina | 83 | 2050-2060 | |
| 97 | César Cruz | 82 | 2046-2048 | |
| 98 | Gabriel Ortíz | 80 | 2032-2035 | |
| 99 | Luis León | 79 | 2052-2060 | |
| 100 | Howard Laverty | 78 | 2023-2031 |
