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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OAVG | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Barry Zito | .0000 | 2000-2018 | |
| 1 | John Zellmer | .0000 | 2007-2015 | |
| 1 | George Zaragoza | .0000 | 2009-2019 | |
| 1 | Carlos Zambrano | .0000 | 2001-2010 | |
| 1 | Cy Young* | .0000 | 1899-1910 | |
| 1 | Early Wynn* | .0000 | 1949-1963 | |
| 1 | Jamey Wright | .0000 | 1996-2007 | |
| 1 | Tim Worrell | .0000 | 1993-2006 | |
| 1 | Kerry Wood | .0000 | 1998-2009 | |
| 1 | Randy Wolf | .0000 | 1999-2011 | |
| 1 | Jay Witasick | .0000 | 1996-2008 | |
| 1 | George Wise | .0000 | 2015-2022 | |
| 1 | Paul Wilson | .0000 | 1996-2007 | |
| 1 | Kris Wilson | .0000 | 2000-2012 | |
| 1 | Vic Willis* | .0000 | 1906-1910 | |
| 1 | Dontrelle Willis | .0000 | 2003-2015 | |
| 1 | Woody Williams | .0000 | 1993-2006 | |
| 1 | Jerome Williams | .0000 | 2003-2010 | |
| 1 | Dave Williams | .0000 | 2001-2013 | |
| 1 | Hoyt Wilhelm* | .0000 | 1957-1971 | |
| 1 | Bob Wickman | .0000 | 1992-2006 | |
| 1 | Dan Wheeler | .0000 | 2003-2017 | |
| 1 | Kip Wells | .0000 | 1999-2011 | |
| 1 | David Wells | .0000 | 1987-2004 | |
| 1 | Brandon Webb | .0000 | 2003-2020 | |
| 1 | Jered Weaver | .0000 | 2006-2018 | |
| 1 | Jeff Weaver | .0000 | 1999-2011 | |
| 1 | David Weathers | .0000 | 1991-2005 | |
| 1 | Jarrod Washburn | .0000 | 1998-2009 | |
| 1 | Tim Wakefield | .0000 | 1992-2006 | |
| 1 | Adam Wainwright | .0000 | 2005-2020 | |
| 1 | Ryan Wagner | .0000 | 2003-2020 | |
| 1 | Ron Villone | .0000 | 1995-2006 | |
| 1 | Oscar Villarreal | .0000 | 2003-2022 | |
| 1 | Justin Verlander | .0000 | 2007-2013 | |
| 1 | Javier Vazquez | .0000 | 2004-2016 | |
| 1 | Jason Vargas | .0000 | 2006-2016 | |
| 1 | Claudio Vargas | .0000 | 2005-2016 | |
| 1 | James Vanleuven | .0000 | 2011-2022 | |
| 1 | Jose Valverde | .0000 | 2003-2016 | |
| 1 | Merkin Valdez | .0000 | 2004-2018 | |
| 1 | Ismael Valdes | .0000 | 1994-2006 | |
| 1 | Lino Urdaneta | .0000 | 2005-2019 | |
| 1 | Ugueth Urbina | .0000 | 2001-2013 | |
| 1 | Steve Trachsel | .0000 | 1993-2005 | |
| 1 | Wade Townsend | .0000 | 2008-2019 | |
| 1 | Brett Tomko | .0000 | 1997-2007 | |
| 1 | Mike Timlin | .0000 | 1991-2007 | |
| 1 | John Thomson | .0000 | 1997-2007 | |
| 1 | Sean Thompson | .0000 | 2008-2015 | |
| 1 | Dale Thayer | .0000 | 2010-2020 | |
| 1 | Julian Tavarez | .0000 | 1993-2005 | |
| 1 | Dennis Tankersley | .0000 | 2002-2012 | |
| 1 | Frank Tanana | .0000 | 1981-1992 | |
| 1 | Brian Szabo | .0000 | 2012-2018 | |
| 1 | Anthony Swarzak | .0000 | 2013-2022 | |
| 1 | Don Sutton* | .0000 | 1981-1984 | |
| 1 | Jeff Suppan | .0000 | 1995-2009 | |
| 1 | Huston Street | .0000 | 2008-2020 | |
| 1 | Cory Stewart | .0000 | 2007-2014 | |
| 1 | Wardell Starling | .0000 | 2005-2018 | |
| 1 | Mike Stanton | .0000 | 1989-2005 | |
| 1 | James Stahl | .0000 | 2010-2022 | |
| 1 | Tim Spooneybarger | .0000 | 2001-2016 | |
| 1 | Justin Spearman | .0000 | 2012-2020 | |
| 1 | Steve Sparks | .0000 | 1998-2004 | |
| 1 | Jeremy Sowers | .0000 | 2005-2016 | |
| 1 | Rafael Soriano | .0000 | 2002-2015 | |
| 1 | Seung Song | .0000 | 2006-2017 | |
| 1 | John Smoltz | .0000 | 1988-2006 | |
| 1 | Jimmy Silver | .0000 | 2007-2015 | |
| 1 | Carlos Silva | .0000 | 2002-2013 | |
| 1 | Eduardo Sierra | .0000 | 2008-2018 | |
| 1 | Andrew Sides | .0000 | 2009-2019 | |
| 1 | Paul Shuey | .0000 | 1994-2007 | |
| 1 | Masakatsu Shoko | .0000 | 2007-2017 | |
| 1 | Steve Shell | .0000 | 2007-2018 | |
| 1 | Ben Sheets | .0000 | 2001-2011 | |
| 1 | Mark Seyler | .0000 | 2012-2022 | |
| 1 | Jae Weong Seo | .0000 | 2002-2008 | |
| 1 | Aaron Sele | .0000 | 1993-2004 | |
| 1 | Tom Seaver* | .0000 | 1977-1986 | |
| 1 | Jason Schmidt | .0000 | 1995-2008 | |
| 1 | Curt Schilling | .0000 | 1988-2006 | |
| 1 | John Sawin | .0000 | 2006-2021 | |
| 1 | Dennis Sarfate | .0000 | 2007-2018 | |
| 1 | Johan Santana | .0000 | 2000-2013 | |
| 1 | Humberto Sanchez | .0000 | 2008-2020 | |
| 1 | C.C. Sabathia | .0000 | 2001-2018 | |
| 1 | Kirk Saarloos | .0000 | 2002-2012 | |
| 1 | Nolan Ryan* | .0000 | 1980-1991 | |
| 1 | Babe Ruth* | .0000 | 1914-1919 | |
| 1 | Glendon Rusch | .0000 | 1997-2008 | |
| 1 | Red Ruffing* | .0000 | 1924-1930 | |
| 1 | Kirk Rueter | .0000 | 1997-2004 | |
| 1 | Celso Rondon | .0000 | 2007-2021 | |
| 1 | Kenny Rogers | .0000 | 1989-2005 | |
| 1 | Rafael Rodriguez | .0000 | 2009-2019 | |
| 1 | Francisco Rodriguez | .0000 | 2002-2018 | |
| 1 | Felix Rodriguez | .0000 | 1995-2009 |
