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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Duane Stewart# | 12.211 | 2062-2066 | |
| 2 | Alex Daniels# | 11.337 | 2053-2066 | |
| 3 | António González | 10.945 | 2039-2052 | |
| 4 | Randy Johnson* | 10.786 | 1989-2006 | |
| 5 | Frederic Korman | 10.629 | 2012-2025 | |
| 6 | Pedro Martinez* | 10.558 | 1992-2009 | |
| 7 | Kerry Wood | 10.411 | 1998-2009 | |
| 8 | Armando Benitez | 10.396 | 1994-2010 | |
| 9 | Yasutake Okuno | 10.360 | 2036-2045 | |
| 10 | Stanley Desimone# | 10.314 | 2052-2066 | |
| 11 | Sal Brower | 10.283 | 2006-2020 | |
| 12 | Jorge Vázquez | 10.275 | 2043-2056 | |
| 13 | Iemitsu Shimaoka | 10.245 | 2036-2042 | |
| 14 | Alex Gibbs | 10.200 | 2046-2059 | |
| 15 | Domingo Fernández | 10.197 | 2046-2053 | |
| 16 | Tony Townsend | 10.188 | 2038-2048 | |
| 17 | Joe Mason | 10.164 | 2032-2046 | |
| 18 | Brent Ansell | 10.129 | 2008-2020 | |
| 19 | Ron Parker# | 10.080 | 2058-2066 | |
| 20 | Sidney Barreiro | 10.060 | 2008-2015 | |
| 21 | Freddy Román | 10.013 | 2028-2041 | |
| 22 | Antonio Reno* | 10.010 | 2009-2024 | |
| 23 | Geronimo Guerro* | 10.000 | 2012-2029 | |
| 24 | Ben Summers | 9.990 | 2034-2044 | |
| 25 | Ken Smith | 9.969 | 2031-2045 | |
| 26 | James Stahl | 9.899 | 2010-2022 | |
| 27 | Oliver Perez | 9.890 | 2002-2015 | |
| 28 | Ernesto Matos* | 9.813 | 2035-2052 | |
| 29 | Octavio Dotel | 9.796 | 1999-2011 | |
| 30 | Robb Nen | 9.751 | 1993-2005 | |
| 31 | Eddy Rodriguez | 9.728 | 2008-2019 | |
| 32 | Terry Jara | 9.706 | 2024-2039 | |
| 33 | Patrick Guilfolly* | 9.694 | 2034-2051 | |
| 34 | Luis Antonio Núñez | 9.692 | 2031-2038 | |
| 35 | Ernesto Nava# | 9.675 | 2055-2066 | |
| 35 | Juan Soto | 9.675 | 2036-2056 | |
| 37 | Mike Hill# | 9.674 | 2058-2066 | |
| 38 | Jose Valverde | 9.666 | 2003-2016 | |
| 39 | Matt Mantei | 9.638 | 1995-2013 | |
| 40 | Dave Brown | 9.635 | 2045-2059 | |
| 41 | Jeff Nelson | 9.634 | 1992-2006 | |
| 42 | John Zinn | 9.605 | 2019-2034 | |
| 43 | Ryan Wagner | 9.584 | 2003-2020 | |
| 44 | Tony Venegas | 9.570 | 2011-2024 | |
| 45 | Lawrence Hodge | 9.555 | 2007-2020 | |
| 46 | Louis-Félix Roy# | 9.551 | 2052-2066 | |
| 47 | Francisco Liriano | 9.547 | 2006-2022 | |
| 48 | Luis Sepúlveda# | 9.546 | 2059-2066 | |
| 49 | Emory Osborn | 9.492 | 2026-2044 | |
| 50 | Ugueth Urbina | 9.479 | 2001-2013 | |
| 51 | Nolan Ryan* | 9.477 | 1980-1991 | |
| 52 | John Gibson | 9.464 | 2018-2024 | |
| 53 | Tony Simmons* | 9.436 | 2033-2051 | |
| 54 | José Manuel | 9.414 | 2036-2051 | |
| 55 | Juan Rodríguez | 9.403 | 2044-2063 | |
| 56 | Jorge Fernández | 9.378 | 2047-2060 | |
| 57 | Yuujin Seiichi | 9.377 | 2015-2031 | |
| 57 | Woody Baker# | 9.377 | 2058-2066 | |
| 59 | Mark Prior* | 9.366 | 2002-2019 | |
| 60 | Robinson Luna | 9.360 | 2036-2057 | |
| 61 | Raúl Alvarado* | 9.345 | 2029-2050 | |
| 62 | Mark Ferrell# | 9.339 | 2056-2066 | |
| 63 | Lyndon Badger# | 9.337 | 2047-2066 | |
| 64 | David Homer# | 9.300 | 2053-2065 | |
| 65 | Trevor Hoffman | 9.299 | 1993-2008 | |
| 66 | Randolph Clark# | 9.258 | 2059-2066 | |
| 67 | Marc Charles | 9.256 | 2038-2048 | |
| 68 | Salvador Sánchez | 9.250 | 2041-2052 | |
| 69 | Ken Turner | 9.242 | 2052-2065 | |
| 70 | Jesse Bashaw# | 9.241 | 2050-2066 | |
| 71 | Juan Heredia# | 9.232 | 2056-2066 | |
| 72 | Jorge López# | 9.221 | 2054-2066 | |
| 73 | Adam Oyola | 9.204 | 2023-2036 | |
| 74 | Erubiel Cueto | 9.199 | 2008-2018 | |
| 75 | Will Gaston# | 9.172 | 2057-2066 | |
| 76 | Irwin Spears* | 9.151 | 2034-2056 | |
| 77 | Wes Papineau | 9.150 | 2017-2031 | |
| 78 | Ronald Johnson | 9.149 | 2024-2035 | |
| 79 | Iván Gómez | 9.147 | 2047-2052 | |
| 80 | Ricky Nolasco | 9.140 | 2008-2019 | |
| 81 | Charles Huntsman | 9.133 | 2011-2022 | |
| 82 | Conner O'Keefe# | 9.131 | 2061-2066 | |
| 83 | Xun Yo# | 9.129 | 2055-2066 | |
| 84 | Mark Kron | 9.127 | 2024-2033 | |
| 85 | Francisco Rodriguez | 9.119 | 2002-2018 | |
| 86 | Roberto García | 9.108 | 2032-2043 | |
| 87 | Thomas Diamond* | 9.102 | 2008-2021 | |
| 88 | Steve Hillery | 9.095 | 2016-2034 | |
| 89 | Gaby Garza* | 9.090 | 2011-2034 | |
| 90 | Salvador Ibarra* | 9.080 | 2040-2058 | |
| 91 | Eric Gagne | 9.078 | 1999-2015 | |
| 92 | Frank Knott# | 9.076 | 2063-2066 | |
| 93 | Ernest Carney | 9.073 | 2050-2063 | |
| 94 | Barney Doyle | 9.054 | 2037-2052 | |
| 95 | Elton Camp | 9.053 | 2050-2060 | |
| 96 | Wayne Clay | 9.050 | 2035-2052 | |
| 96 | Mo-ruo Fang# | 9.050 | 2054-2066 | |
| 98 | Michael Slone | 9.039 | 2014-2028 | |
| 99 | Andrew Smith | 9.035 | 2038-2051 | |
| 100 | Justin Verlander | 9.029 | 2007-2013 |
