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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Scott Fitzpatrick | 5920.0 | 2038-2060 | |
| 2 | Corey McDonald* | 5363.0 | 2031-2052 | |
| 3 | Gaby Garza* | 5304.0 | 2011-2034 | |
| 4 | Alfredo Perez* | 5303.0 | 2012-2037 | |
| 5 | Amando Demony* | 5208.1 | 2031-2053 | |
| 6 | Steve Carlton* | 5041.0 | 1965-1988 | |
| 7 | Arthur Breckenridge* | 4974.2 | 2016-2038 | |
| 8 | José Álvarez# | 4970.1 | 2046-2066 | |
| 9 | Phil Niekro* | 4878.0 | 1966-1987 | |
| 10 | Teodoro Erazo* | 4840.0 | 2017-2040 | |
| 11 | César Salinas# | 4688.1 | 2046-2066 | |
| 12 | Roger Clemens* | 4660.2 | 1984-2005 | |
| 13 | Salvador Ibarra* | 4623.0 | 2040-2058 | |
| 14 | Robin Roberts | 4577.0 | 1948-1965 | |
| 15 | Greg Hill* | 4550.0 | 2037-2056 | |
| 16 | Ching Lung Lo | 4502.2 | 2006-2028 | |
| 17 | Greg Miller* | 4500.2 | 2006-2023 | |
| 18 | Eppa Rixey* | 4494.0 | 1912-1933 | |
| 19 | Bert Blyleven | 4461.0 | 1970-1988 | |
| 20 | Roland Noyola* | 4455.0 | 2009-2027 | |
| 21 | Gerardo García* | 4422.0 | 2033-2051 | |
| 22 | Juan Rodríguez | 4419.1 | 2044-2063 | |
| 23 | Freddy Rodríguez | 4406.0 | 2035-2053 | |
| 24 | Robert Sayler | 4383.0 | 2016-2037 | |
| 25 | Doug Bennett | 4366.1 | 2042-2061 | |
| 26 | Leland Patterson | 4355.2 | 2030-2050 | |
| 26 | Salvador Rangel | 4355.2 | 2027-2048 | |
| 28 | Earl French* | 4353.2 | 2031-2048 | |
| 29 | Alfred Fellers* | 4317.1 | 2009-2027 | |
| 30 | William Hill | 4294.0 | 2029-2048 | |
| 31 | Nick Kelly* | 4264.2 | 2034-2054 | |
| 32 | Edwin Jackson* | 4251.2 | 2003-2022 | |
| 33 | Charles West | 4241.0 | 2039-2056 | |
| 34 | Jeffrey Bancroft | 4221.0 | 2041-2058 | |
| 35 | Roberto Rivera | 4180.0 | 2030-2050 | |
| 36 | Neill Oulton* | 4159.2 | 2038-2054 | |
| 37 | Mark Prior* | 4146.1 | 2002-2019 | |
| 38 | Leon Rodriguez* | 4145.0 | 2019-2037 | |
| 39 | Carl Richardson | 4141.2 | 2034-2055 | |
| 40 | Greg Maddux* | 4122.1 | 1986-2004 | |
| 41 | Cam Briggs* | 4102.0 | 2031-2050 | |
| 42 | Miguel Duran | 4070.1 | 2017-2034 | |
| 43 | Jesse Bashaw# | 4066.0 | 2050-2066 | |
| 44 | Shinsui Kichida | 3979.2 | 2032-2049 | |
| 45 | Hai Fons | 3968.1 | 2010-2029 | |
| 46 | Jim Palmer* | 3948.0 | 1965-1984 | |
| 47 | Jerry Smith | 3947.0 | 2017-2034 | |
| 48 | Rubén González | 3917.0 | 2033-2051 | |
| 49 | Bob Gibson | 3885.0 | 1959-1975 | |
| 50 | Travis Alexander | 3884.0 | 2036-2053 | |
| 50 | Higinio Bueno | 3884.0 | 2022-2039 | |
| 52 | Dan Miller | 3883.2 | 2033-2049 | |
| 53 | Cy Young* | 3877.0 | 1899-1910 | |
| 54 | Rubén Rodríguez# | 3871.1 | 2046-2065 | |
| 55 | Bob Feller* | 3828.0 | 1936-1956 | |
| 56 | Teinosuke Maekawa* | 3823.1 | 2031-2048 | |
| 57 | Mike Beasley# | 3813.1 | 2050-2066 | |
| 58 | Ramón Gómez | 3803.0 | 2036-2052 | |
| 59 | Steve Hillery | 3799.0 | 2016-2034 | |
| 60 | Joel Pineiro | 3798.2 | 2000-2018 | |
| 61 | César Mendoza* | 3791.1 | 2032-2048 | |
| 62 | Manuel González* | 3772.0 | 2039-2053 | |
| 63 | Paul Carvalho | 3754.2 | 2023-2040 | |
| 64 | Luke Bone | 3733.2 | 2013-2033 | |
| 65 | Román Pérez | 3703.2 | 2029-2045 | |
| 66 | Tom Glavine* | 3699.1 | 1987-2004 | |
| 67 | Gerald Donaldson* | 3697.0 | 2010-2029 | |
| 68 | William Benefiel* | 3694.1 | 2023-2036 | |
| 69 | Curtis Pineda | 3690.0 | 2015-2030 | |
| 70 | Royce Roberts | 3686.0 | 2034-2051 | |
| 71 | Roy Halladay | 3668.0 | 1998-2016 | |
| 72 | Xavier López | 3623.2 | 2042-2058 | |
| 73 | Desmond Greenwood | 3616.2 | 2045-2061 | |
| 74 | Santiago Torres | 3615.1 | 2027-2043 | |
| 75 | Mike Mussina | 3603.0 | 1991-2007 | |
| 76 | Randy Johnson* | 3581.1 | 1989-2006 | |
| 77 | Jame Raskin | 3567.1 | 2017-2033 | |
| 78 | Carlos Olivos | 3556.2 | 2031-2047 | |
| 79 | John Keller | 3552.1 | 2047-2065 | |
| 80 | Jim Bunning* | 3547.0 | 1955-1971 | |
| 81 | Dave Carrizal | 3537.0 | 2038-2055 | |
| 82 | Brandon Webb | 3515.0 | 2003-2020 | |
| 83 | Norberto López* | 3514.2 | 2041-2058 | |
| 84 | José Manuel | 3504.2 | 2036-2051 | |
| 85 | Barry Zito | 3500.2 | 2000-2018 | |
| 86 | Bob Flory | 3498.2 | 2016-2036 | |
| 87 | Tony Palácios | 3494.1 | 2041-2057 | |
| 88 | C.C. Sabathia | 3491.0 | 2001-2018 | |
| 89 | Stanley Desimone# | 3487.2 | 2052-2066 | |
| 90 | Dustin McGowan | 3482.1 | 2004-2020 | |
| 91 | Fred Swain | 3475.2 | 2025-2044 | |
| 92 | Sergio Chavarriaga | 3454.1 | 2027-2042 | |
| 93 | Júlio Palma# | 3450.0 | 2050-2066 | |
| 94 | Walter Holub | 3437.0 | 2021-2038 | |
| 95 | Tony Venegas | 3425.0 | 2011-2024 | |
| 96 | Tyler Clippard | 3412.1 | 2006-2022 | |
| 97 | Jeff Johnstone | 3410.0 | 2038-2054 | |
| 98 | Jerry Agee | 3383.2 | 2013-2030 | |
| 99 | Willie Calhoun | 3377.2 | 2022-2039 | |
| 100 | Tony Paylor* | 3375.1 | 2035-2049 |
