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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | CG | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Cy Young* | 391 | 1899-1910 | |
| 2 | Robin Roberts | 303 | 1948-1965 | |
| 3 | Eppa Rixey* | 290 | 1912-1933 | |
| 4 | Bob Feller* | 279 | 1936-1956 | |
| 5 | Pete Alexander* | 267 | 1911-1930 | |
| 6 | Bob Gibson | 255 | 1959-1975 | |
| 7 | Steve Carlton* | 254 | 1965-1988 | |
| 8 | Phil Niekro* | 233 | 1966-1987 | |
| 9 | Bert Blyleven | 231 | 1970-1988 | |
| 10 | Pud Galvin* | 226 | 1886-1892 | |
| 11 | Hal Newhouser* | 212 | 1939-1955 | |
| 12 | Jim Palmer* | 211 | 1965-1984 | |
| 13 | Jesse Haines* | 208 | 1918-1937 | |
| 14 | Stan Coveleski* | 194 | 1916-1924 | |
| 15 | Mickey Lolich | 190 | 1963-1975 | |
| 16 | Bob Lemon* | 188 | 1946-1958 | |
| 17 | Gaylord Perry* | 154 | 1972-1982 | |
| 18 | Jim Bunning* | 146 | 1955-1971 | |
| 19 | Early Wynn* | 144 | 1949-1963 | |
| 20 | Dizzy Dean* | 141 | 1930-1937 | |
| 21 | Scott Fitzpatrick | 131 | 2038-2060 | |
| 22 | Vic Willis* | 120 | 1906-1910 | |
| 23 | Lefty Grove* | 119 | 1934-1941 | |
| 24 | Roger Clemens* | 118 | 1984-2005 | |
| 25 | Catfish Hunter* | 116 | 1965-1974 | |
| 26 | William Benefiel* | 113 | 2023-2036 | |
| 26 | Fergie Jenkins* | 113 | 1965-1981 | |
| 28 | Gerardo García* | 108 | 2033-2051 | |
| 29 | Babe Ruth* | 105 | 1914-1919 | |
| 30 | Greg Maddux* | 103 | 1986-2004 | |
| 31 | Roland Noyola* | 100 | 2009-2027 | |
| 32 | Jack Chesbro* | 94 | 1899-1909 | |
| 33 | Dennis Eckersley* | 93 | 1975-1998 | |
| 33 | Alfred Fellers* | 93 | 2009-2027 | |
| 35 | Randy Johnson* | 90 | 1989-2006 | |
| 36 | Red Ruffing* | 85 | 1924-1930 | |
| 36 | Curt Schilling | 85 | 1988-2006 | |
| 38 | Greg Miller* | 84 | 2006-2023 | |
| 39 | Freddy Rodríguez | 83 | 2035-2053 | |
| 40 | Burleigh Grimes* | 75 | 1916-1931 | |
| 41 | Kevin Brown | 73 | 1986-2005 | |
| 41 | Herb Pennock* | 73 | 1915-1934 | |
| 43 | Charles West | 70 | 2039-2056 | |
| 44 | Rubén González | 68 | 2033-2051 | |
| 45 | Neill Oulton* | 67 | 2038-2054 | |
| 45 | Manuel Soto | 67 | 2048-2058 | |
| 47 | Amando Demony* | 64 | 2031-2053 | |
| 48 | Alfredo Perez* | 63 | 2012-2037 | |
| 49 | Jeffrey Bancroft | 62 | 2041-2058 | |
| 49 | Higinio Bueno | 62 | 2022-2039 | |
| 51 | Mike Mussina | 60 | 1991-2007 | |
| 52 | Mary Hiltner | 59 | 2018-2034 | |
| 52 | Waite Hoyt* | 59 | 1919-1936 | |
| 52 | Victor Powell | 59 | 2041-2058 | |
| 52 | Charles Radbourn* | 59 | 1890-1891 | |
| 56 | Chris Ashling# | 58 | 2056-2066 | |
| 56 | Doug Bennett | 58 | 2042-2061 | |
| 56 | Ronald Garnica | 58 | 2014-2026 | |
| 56 | James Rogers | 58 | 2048-2060 | |
| 60 | Tim Long | 57 | 2036-2051 | |
| 61 | David Cone | 56 | 1986-2004 | |
| 61 | Dan Miller | 56 | 2033-2049 | |
| 61 | Kid Nichols* | 56 | 1904-1906 | |
| 61 | Dan White | 56 | 2029-2045 | |
| 65 | Mike Beasley# | 55 | 2050-2066 | |
| 65 | James Johnson | 55 | 2007-2021 | |
| 65 | Rubén Rodríguez# | 55 | 2046-2065 | |
| 68 | Walter Holub | 54 | 2021-2038 | |
| 68 | Salvador Ibarra* | 54 | 2040-2058 | |
| 68 | Román Pérez | 54 | 2029-2045 | |
| 68 | Tony Venegas | 54 | 2011-2024 | |
| 68 | David Wells | 54 | 1987-2004 | |
| 73 | Jesse Bashaw# | 53 | 2050-2066 | |
| 73 | Curtis Pineda | 53 | 2015-2030 | |
| 73 | Daniel Walther | 53 | 2024-2039 | |
| 76 | Earnest Evans | 52 | 2041-2054 | |
| 76 | Tom Glavine* | 52 | 1987-2004 | |
| 78 | Sergio Chavarriaga | 51 | 2027-2042 | |
| 78 | Scott Erickson | 51 | 1990-2004 | |
| 78 | Earl French* | 51 | 2031-2048 | |
| 78 | Nolan Ryan* | 51 | 1980-1991 | |
| 78 | Frank Tanana | 51 | 1981-1992 | |
| 83 | Roy Halladay | 50 | 1998-2016 | |
| 84 | Leland Patterson | 49 | 2030-2050 | |
| 84 | César Salinas# | 49 | 2046-2066 | |
| 84 | Tom Seaver* | 49 | 1977-1986 | |
| 84 | Barry Zito | 49 | 2000-2018 | |
| 88 | Jerry Agee | 48 | 2013-2030 | |
| 88 | Koshichirou Hidetora | 48 | 2025-2037 | |
| 88 | Tim Keefe* | 48 | 1892-1893 | |
| 91 | John Girton | 47 | 2021-2034 | |
| 91 | John Smoltz | 47 | 1988-2006 | |
| 93 | Terry Mulholland | 46 | 1986-2003 | |
| 93 | Mark Prior* | 46 | 2002-2019 | |
| 93 | Phil Vinson | 46 | 2042-2054 | |
| 96 | William Hill | 45 | 2029-2048 | |
| 96 | Marty Scott | 45 | 2030-2043 | |
| 98 | Mark Buehrle | 44 | 2000-2015 | |
| 98 | Mark Mulder | 44 | 2000-2013 | |
| 100 | Albert Castro# | 43 | 2052-2065 |
